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Outside Variant Resources
Resources
Wiki:
https://github.com/corradin-lab/outside-variants/wiki/Theoretical-framework--Important-concepts
Code:
https://github.com/corradin-lab/outside-variants
Publications:
Cell type specific intralocus interactions reveal oligodendrocyte mechanisms in MS. Cell (2020).
Modeling disease risk through analysis of physical interactions between genetic variants within chromatin regulatory circuitry. Nature Genetics (2016).
PreSTIGE Resources
Predicting Specific Tissue Interactions between Genes and Enhancers
Prediction Database:
https://genetics.cwru.edu/prestige/
Homer page to generate new predictions
prestige.case.edu
Publications:
Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits. Genome Research (2014).
Comparison Reveals Activation of "Seed" Enhancers during Transition from Naive to Primed Pluripotency. Cell Stem Cell (2014).
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